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Aquaporin Channel Mini Model
Aquaporin Channel Mini Model
Aquaporin Channel Mini Model


 
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Starting at: $84.00

Grade Levels
High School
Undergraduate

Warnings
Choking Hazard
Small Magnets
Science Education Product
California Proposition 65



Quantity in Stock:(Out of Stock)
Availability: Discontinued
Product Code: ACMM
This Item is currently Not for Sale

Description Contents Teacher Resources
 

This plaster mini model is being discontinued as we redesign it for 3D printing in a larger size and a more durable material. Best of all, we believe we will be able to offer it at a lower price! Watch for its updated availability on our Facebook page, Instagram, and eNewsletter.

Don’t just tell your students how aquaporin moves water across a lipid bilayer. Show them its structure and discuss its function with our colorful 3-D protein model.

Water molecules rapidly flow in single file through the aquaporin channel – a membrane-spanning protein. Its structure consists of 6 alpha helices and 2 half alpha helices that form an hourglass shape through which water molecules move one at a time. Two asparagine amino acids are strategically positioned at the narrowest point of the hourglass and provide selectivity to this channel, allowing only water molecules to pass through. While the process is not fully understood, many researchers believe that the water molecules roll over as they bind with the asparagine.

The 2003 Nobel Prize in Chemistry was awarded "for discoveries concerning channels in cell membranes" jointly with one half to Peter Agre "for the discovery of water channels" and with one half to Roderick MacKinnon "for structural and mechanistic studies of ion channels".

This 3.75'' model is made of plaster by rapid prototyping and should be handled with care. Mini models will break if dropped, held tightly or handled roughly. Its PDB file is 1FQY.pdb.


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