Model how the Cas9 protein is programmed with RNA to search
for and identify specific sequences of DNA before making the double-stranded
cut. Explore and discuss how Cas9 is being engineered with new
features that make it a useful tool for editing the human genome. With the kit's colorful foam pieces and placemat your students can:
1-Group Set Content
1 Foldable Placemat*6 White sticky-back Cas9 parts2 White Nuclease parts5 Orange tracr RNA pieces1 Black Spacer RNA piece40 Red Adenine (A) DNA Nucleotides40 Yellow Thymine (T) DNA Nucleotides40 Green Guanine (G) DNA Nucleotides40 Blue Cytosine (C) DNA Nucleotides40 Purple RNA Nucleotides (10 each of A, U, G & C)40 Tan RNA Nucleotides (10 each of A, U, G & C)40 Blue RNA Nucleotides (10 each of A, U, G & C)1 Gray Tetraloop1 Gray Cytosine Deanimase
*Placemat may be folded in half (printing out) before applying the sticky-back foam to make storage in the box easier. Or leave the placemat flat and store outside of box. See Assembly Instructions for more information.
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