This plaster mini model is being discontinued as we redesign it for 3D printing in a larger size and a more durable material. Best of all, we believe we will be able to offer it at a lower price! Watch for its updated availability on our Facebook page, Instagram, and eNewsletter.

Transfer RNA (tRNA) is a vital component in the translation process. Our 3-D tRNA Mini Models will help your students understand how its structure enables tRNA to perform its important role in protein synthesis.

Transfer RNAs (tRNA) are short RNA molecules (76 nucleotides) that deliver amino acids to the ribosome, where they join to a growing peptide chain during protein synthesis. Transfer RNAs fold into 3-D structures, stabilized by hydrogen bonding between complementary bases. Individual amino acids are joined to the 3’-end of the tRNA. On the other side of the molecule is the anticodon. This is the portion of the tRNA that recognizes the triplet codons on the messenger RNA (mRNA). In 1964, Robert Holley isolated and determined the structure of tRNA. Just 4 years later, he was awarded the 1968 Nobel Prize in Physiology or Medicine, a prize he shared with H. Gobind Khorana and Marshall Nirenberg; all 3 greatly contributed to the areas of transcription and translation.

In the plaster 3-D model, the tRNA protein is shown in spacefill format. The phosphate backbone of the tRNA is white, the 4 bases are red, the anticodon is blue, and the 3’-end (where the amino acid is bound) is yellow. The white, nylon, alpha carbon backbone model shows additional details not seen on the plaster model.

To date 31 researchers have been awarded Nobel Prizes for their investigations of RNA, spanning 50 years from 1959 to 2009.

Both 3.5'' models are made on rapid prototyping machines and should be handled with care. Mini models will break if dropped, held tightly or handled roughly, although nylon models are less likely to break than plaster models. Their PDB file is 4TNA.pdb.